Peer-reviewed papers
3- Morsi NG1, Ali SM , Elsonbaty SS , Afifi AA , Hamad MA , Gao H , Elsabahy M , Poly(glycerol methacrylate)-based degradable nanoparticles for delivery of small interfering RNA, Pharmaceutical Development and Technology, 1-13 DOI: 10.1080/10837450.2017.1312443. , (2017).
2- Abdelkader A, El-Mokhtar MA, Abdelkader O, Hamad MA, Elsabahy M, El-Gazayerly ON. , Ultrahigh antibacterial efficacy of meropenem-loaded chitosan nanoparticles in a septic animal model, Carbohydrate Polymers 174, 1041-1050 ,DOI: 10.1016/j.carbpol.2017.07.030 , (2017).
1- Abdelkader A, El-Mokhtar MA, Abdelkader O, Hamad MA, Elsabahy M, El-Gazayerly ON. , Development and in vivo evaluation of chitosan beads for the colonic delivery of azathioprine for treatment of inflammatory bowel disease , European Journal of Pharmaceutical Sciences 109, 269-279 ,DOI: 10.1016/j.ejps.2017.08.025, (2017).
1- Abdelkader A, El-Mokhtar MA, Abdelkader O, Hamad MA, Elsabahy M, El-Gazayerly ON. , Development and in vivo evaluation of chitosan beads for the colonic delivery of azathioprine for treatment of inflammatory bowel disease , European Journal of Pharmaceutical Sciences 109, 269-279 ,DOI: 10.1016/j.ejps.2017.08.025, (2017).
4- Nourhan K. Mohamed , Mostafa A. Hamad , Mohamed Z.E. Hafez , Karen L. Wooley Mahmoud Elsabahy , Nanomedicine in management of hepatocellular carcinoma: Challenges and opportunities., International journal of cancer 140 (7), 1475-1484 , (2017).
5- Hebatallah B. Mohamed, Sohair M. El-Shanawany, Mostafa A. Hamad, Mahmoud Elsabahy, Niosomes: A Strategy toward Prevention of Clinically Significant Drug Incompatibilities, Scientific Reports 7, doi:10.1038/s41598-017-06955-w. , (2017).
6- Elzeny H, Zhang F, Ali EN, Fathi HA, Zhang S, Li R, El-Mokhtar MA, Hamad MA, Wooley KL, Elsabahy M, Polyphosphoester nanoparticles as biodegradable platform for delivery of multiple drugs and siRNA, Drug design, development and therapy, 11, 483-496, doi: 10.2147/DDDT.S128503. , (2017).
7- Aml I Mekkawy, Mohamed A El-Mokhtar, Nivien A Nafady, Naeima Yousef, Mostafa A Hamad, Sohair M El-Shanawany, Ehsan H Ibrahim, Mahmoud Elsabahy, In vitro and in vivo evaluation of biologically synthesized silver nanoparticles for topical applications: effect of surface coating and loading into hydrogels., International Journal of Nanomedicine, 12, 759-777, DOI : 10.2147/IJN.S124294, (2017).
8- Ebtehal Ahmed, Nasser Anwar, Omyma Galal, Mahmoud Elsabahy, Mokhtar Taha, Gastroprotective potential of melatonin versus melatonin loaded niosomes on gastric ulcer healing in rats, Comparative Clinical Pathology, 26(1), 35-50, DOI : 10.1007/s00580-016-2344-8, (2017).
9- Young H Lim, Kristin M Tiemann, David A Hunstad, Mahmoud Elsabahy, Karen L Wooley, Polymeric nanoparticles in development for treatment of pulmonary infectious diseases, Wiley Interdisciplinary Reviews: Nanomedicine and NanobiotechnologyDOI: 10.1002/wnan.1401, (2016
10- Sangho Cho, Gyu Seong Heo, Sarosh Khan, Amelia M. Gonzalez, Mahmoud Elsabahy, and Karen L. Wooley PFunctionalizable Hydrophilic Polycarbonate, Poly(5-methyl-5-(2-hydroxypropyl)aminocarbonyl-1,3-dioxan-2-one), Designed as a Degradable Alternative for PHPMA and PEG. Macromolecules, 115 (19), 10967–11011 , DOI: 10.1021/acs.macromol.5b01974, (2015).
11- Mahmoud Elsabahy, Gyu Seong Heo, Soon-Mi Lim, Guorong Sun, and Karen L. Wooley. Polymeric Nanostructures for Imaging and Therapy. Chemical Reviews, 115 (19), 10967–11011, DOI: 10.1021/acs.chemrev.5b00135, (2015).
"Chemical reviews is the journal no.1 in the world in chemistry"
12- Mahmoud Elsabahy, Karen L Wooley. Data Mining as a Guide for the Construction of Cross-Linked Nanoparticles with Low Immunotoxicity via Control of Polymer Chemistry and Supramolecular Assembly. Accounts of chemical research, DOI: 10.1021/acs.accounts.5b00066 (2015).
13- Fuwu Zhang , Shiyi Zhang , Stephanie F. Pollack , Richen Li , Amelia M. Gonzalez , Jingwei Fan , Jiong Zou , Sarah E. Leininger , Adriana Pavía-Sanders , Rachel Johnson , Laura D. Nelson , Jeffery E. Raymond , Mahmoud Elsabahy , Dennis M. P. Hughes , Mark W. Lenox§, Tiffany P. Gustafson , and Karen L. Wooley Improving Paclitaxel Delivery: In Vitro and In Vivo Characterization of PEGylated Polyphosphoester-Based Nanocarriers. Journal of the American Chemical Society, 137 (5), 2056–2066 (2015).
14- Hirohito Metoki1, Taku Obara, Kei Asayama, Michihiro Satoh, Miki Hosaka, Noha Elnagar, Yoshinori Miyawaki, Iwao Kojima, Takayoshi Ohkubo, and Yutaka Imai for the Japan-Home versus Office Blood Pressure Measurement Evaluation – Augmentation Index Study Investigators. Differential effects of angiotensin II receptor blocker and losartan/hydrochlorothiazide combination on central blood pressure and augmentation index. Clin Exp Hypertens, 2014 Sep 30; DOI: 10.3109/10641963.2014.960972
15- Young Lim, Gyu Seong Heo, Yohannes Rezenom, Stephanie Pollack, Jeffery Raymond, Mahmoud Elsabahy, Karen L. Wooley. Development of a Vinyl Ether-functionalized Polyphosphoester as a Template for Multiple Post-polymerization Conjugation Chemistries and Study of Core Degradable Polymeric Nanoparticles. Macromolecules, 47, 4634-4644 (2014).
16- Jiong Zou, Fuwu Zhang, Shiyi Zhang, Stephanie F. Pollack, Mahmoud Elsabahy, Jingwei Fan, and Karen L. Wooley. Poly(ethylene oxide)-block-polyphosphoester-graft-paclitaxel Conjugates with Acid-labile Linkages as a pH-Sensitive and Functional Nanoscopic Platform for Paclitaxel Delivery.Advanced Healthcare Materials, 3, 441-448 (2014).
17- Noha Elnagar, Michihiro Satoh, Miki Hosaka, Kei Asayama, et al. The velocity of home blood pressure reduction in response to low-dose eplerenone combined with other antihypertensive drugs determined by exponential decay function analysis. Clin Exp Hypertens, 2014; 36(2): 83–91
18- Michihiro Satoh, Noriko Kato, Miki Hosaka, Noha Elnag, et al. Validity of salt intake assessment system based on a 24-h dietary recall method using a touch panel computer Clin Exp Hypertens. 01/2014; DOI:10.3109/10641963.2013.863319
19- Mahmoud Elsabahy, Shiyi Zhang, Fuwu Zhang, Zhou J. Deng, Young H. Lim, Hai Wang, Perouza Parsamian, Paula T. Hammond and Karen L. Wooley*. Surface Charges and Shell Crosslinks Each Play Significant Roles in Mediating Degradation, Biofouling, Cytotoxicity and Immunotoxicity for Polyphosphoester-based Nanoparticles. Scientific Reports, 3, 3313(2013).
“One of the Journals of the Nature Publishing Group”
“Published in collaboration with the Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge”
20- Mahmoud Elsabahy, Ang Li, Fuwu Zhang, Deborah Sultan, Yongjian Liu and Karen L. Wooley*. Differential immunotoxicities of poly(ethylene glycol)- vs. poly(carboxybetaine)-coated nanoparticles. Journal of Controlled Release, 172, 641-652(2013).
21- Mahmoud Elsabahy, Sandani Samarajeewa, Jeffery E. Raymond, Corrie Clark, Karen L. Wooley*. Shell-crosslinked knedel-like nanoparticles induce lower immunotoxicity than their non-crosslinked analogs. Journal of Materials Chemistry B, 1, 5241-5255 (2013).
22- Mahmoud Elsabahy, Ritu Shrestha, Corrie Clark, Sara Taylor, Jeffery Leonard, Karen L. Wooley. Multifunctional Hierarchically Assembled Nanostructures as Complex Stage-Wise Dual-Delivery Systems for Coincidental Yet Differential Trafficking of siRNA and Paclitaxel. Nano Letters,13, 2172-2181 (2013).
23- Shiyi Zhang, Jiong Zou, Mahmoud Elsabahy, Amolkumar Karwa, Ang Li, Dennis A. Moore, Richard B. Dorshow, Karen L. Wooley. Poly(ethylene oxide)-block-polyphosphester-based paclitaxel conjugates as a platform for ultra-high paclitaxel-loaded multifunctional nanoparticles. Chemical Science, 4, 2122-2126 (2013).
24- Fuwu Zhang, Mahmoud Elsabahy, Shiyi Zhang, Lily Yun Lin, Jiong Zou, Karen L. Wooley. Shell crosslinked knedel-like nanoparticles for delivery of cisplatin: Effects of crosslinking. Nanoscale, 5, 3220-3225 (2013).
25- Sandani Samarajeewa, Aida Ibricevic, Sean P. Gunsten, Ritu Shrestha, Mahmoud Elsabahy, Steven L. Brody*, Karen L. Wooley*. Degradable Cationic Shell Crosslinked Knedel-like Nanoparticles: Synthesis, degradation, nucleic acid binding and in vitro evaluation. Biomacromolecules, 14, 1018-1027 (2013).
26- Mahmoud Elsabahy, Marianna Foldvari. Needle-free gene delivery through the skin: an overview of recent strategies. Current Pharmaceutical Design, 41, 7301-7315 (2013).
27- Mahmoud Elsabahy, Karen L. Wooley. Cytokines as biomarkers of nanoparticle immunotoxicity. Chemical Society Reviews, 42, 5552-5576 (2013).
28- Sandani Samarajeewa, Ritu Shrestha, Mahmoud Elsabahy, Amolkumar Karwa, Ang Li, Ryan P. Zentay, James G. Kostelc, Richard B. Dorshow, Karen L. Wooley. In vitro Efficacy of Paclitaxel-loaded Dual-responsive Shell Crosslinked Polymer Nanoparticles Having Orthogonally-degradable Disulfide Crosslinked Corona and Polyester Core Domains. Molecular Pharmaceutics, 10, 1092-1099(2013).
29- Imai Yutaka, Hosaka Miki, Elnagar Noha, Satoh Michihiro. The clinical significance of home blood pressure measurements for the prevention and management of high blood pressure. Clin Exp Hypertens. 2013 Jun 13. doi: 10.1111/1440-1681.1214
30- Shiyi Zhang, Jiong Zou, Fuwu Zhang, Mahmoud Elsabahy, Zhu, J.; Pochan, D. J.; Karen L. Wooley. Rapid and Versatile Construction of Diverse and Functional Nanostructures Derived from a Polyphosphoester-based Biomimetic Block Copolymer System. Journal of the American Chemical Society, 134, 18467-18474 (2012).
31- Ritu Shrestha, Mahmoud Elsabahy, Hannah Luehmann, Sandani Samarajeewa, Stephanie Florez-Malaver, Nam S. Lee, Michael J. Welch, Yongjian Liu*, Karen L. Wooley*. Hierarchically Assembled Theranostic Nanostructures for siRNA Delivery and Imaging Applications. Journal of the American Chemical Society, 134, 17362-17365 (2012).
32- Ritu Shrestha, Mahmoud Elsabahy, Stephanie Florez-Malaver, Sandani Samarajeewa, Karen L. Wooley*. Endosomal escape and siRNA delivery with cationic shell crosslinked knedel-like nanoparticles with tunable buffering capacities. Biomaterials, 33, 8557-8568 (2012).
33- Mahmoud Elsabahy and Karen L. Wooley. Design of polymeric nanoparticles for biomedical delivery applications. ChemInform Abstract, 43, 173 (2012).
34- Mahmoud Elsabahy and Karen L. Wooley. Strategies toward well-defined polymer nanoparticles inspired by nature: chemistry versus versatility. Journal of Polymer Science Part A: Polymer Chemistry, 50, 1869-1880 (2012). “Highlight”
35- Mahmoud Elsabahy and Karen L. Wooley . Design of polymeric nanoparticles for biomedical delivery applications.
Chemical Society Reviews, 41, 2545-2561 (2012).
*Top ten most accessed articles in February, March and April 2012”
“Highlighted and selected for the front cover art and free access for six-weeks”
“Among the top ten most accessed reviews in Chem Soc Rev in 2012 {Chem Soc Rev Editorial – getting back to basics – Chemical Society Reviews, 42, 11-14 (2013)}”
“Among the top 20 articles (number 1) published on the same topic since February 2012 - wipimd.com”
“Highly cited by scholars: Better than 97% of items indexed by Web of Science in 2012”
36- Hui Gao, Mahmoud Elsabahy, Elisabeth Giger, Jianbiao Ma, Robert E. Prud’homme and Jean-Christophe Leroux. Self assembling properties of aminated poly(glycerol methacrylate)s. Journal of Controlled Release, 152, e133-e191, (2011).
37- Arnaud E. Felber, Bastien Castagner, Mahmoud Elsabahy, Glen F. Deleavey, Masad J. Damhaand Jean-Christophe Leroux.siRNA nanocarriers based on methacrylic acid copolymers.Journal of Controlled Release, 152, 159-167, (2011).
38- Mahmoud Elsabahy and Marianna Foldvari. Nanotechnology enables superior medical therapies. Current Drug Delivery, editorial, 8, 225-226 (2011).
39- Mahmoud Elsabahy, Adil Nazarali and Marianna Foldvari. Non-viral nucleic acid delivery: Key challenges and future directions. Current Drug Delivery, 8, 235-244 (2011).
40- McDonald Donkuru, Ildiko Badea, Shawn Wettig, Ronald Verrall, Mahmoud Elsabahy and Marianna Foldvari, Advancing non-viral gene delivery:Lipid- and surfactant-based nanoparticle design strategies. Nanomedicine (Lond)5, 1103-1127 (2010).
41- Hui Gao, Mahmoud Elsabahy, Elisabeth Giger, Dekun Li, Robert E. Prud’homme and Jean-Christophe Leroux. Aminated linear and star-shape poly(glycerol methacrylate)s: synthesis and self-assembling properties. Biomacromolecules11, 889-895, (2010).
42- Mahmoud Elsabahy, Nada Wazen, Núria Bayó-Puxan, Glen Deleavey, Marc Servant, Masad J. Damha and Jean-Christophe Leroux. Delivery of nucleic acids through the controlled disassembly of multifunctional nanocomplexes.Advanced Functional Materials19, 3862–3867 (2009).
43- Marie-Hélène Dufresne, Mahmoud Elsabahy and Jean-Christophe Leroux, Characterization of polyion complex micelles designed to address the challenges of oligonucleotide delivery. Pharmaceutical Research25,2083-2093 (2008).
44- Mahmoud Elsabahy, Mingzhen Zhang, Shao-Ming Gan, Karen C. Waldronand Jean-Christophe Leroux, Synthesis and enzymatic stability of PEGylated oligonucleotide duplexes and their self-assemblies with polyamidoamine dendrimers. Soft Matter4, 294-302 (2008).
37. Mahmoud Elsabahy, Marie-Ève Perron, Nicolas Bertrand, Ga-er Yuand Jean-Christophe Leroux, Solubilization of docetaxel in poly(ethylene oxide)-block-poly(butylene/styrene oxide) micelles. Biomacromolecules 8, 2250-2257 (2007).
Development and optimization of albendazole nanosuspension as local adjuvant therapy for treatment of Enterobiasis
A Mekkawy, G Fetih, M El-Badry, A Allam
Bulletin of Pharmaceutical Sciences. Assiut
Electrospun vancomycin-loaded nanofibers for management of methicillin-resistant Staphylococcus aureus-induced skin infections
Heba A.Fathia1 AyatAbdelkadera1 Mahmoud S. AbdelKarimbAyman A.Abdelazizc Mohamed A.El-Mokhtard AyatAllame GihanFetihae MahmoudEl Badryae MahmoudElsabahyaef
International Journal of Pharmaceutics 586, 119620
Performance of Curcumin in Nanosized Carriers Niosomes and Ethosomes as Potential Anti-MM El-Mahdy, AS Hassan, M El-Badry, GEDA El-Gindy
Bulletin of Pharmaceutical Sciences. Assiut 43 (1), 105-122
Inflammatory Delivery System for Topical Application
Self-Emulsifying Drug Delivery Systems: Easy to Prepare Multifunctional Vectors for Efficient Oral Delivery
K AboulFotouh, AA Allam, M El-Badry
Current and Future Aspects of Nanomedicine